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Clinical endpoints in trials of chemoradiation for patients with anal cancer.

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HPV vaccine against anal HPV infection and anal intraepithelial neoplasia.

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Comment in N Engl J Med. Dis Colon Rectum. Caused by infection with human papillomavirus HPV , primarily HPV type 16 or 18, anal cancer is preceded by high-grade anal intraepithelial neoplasia grade 2 or 3.

Consumption of red-hot chili pepper increases symptoms in patients with acute anal fissures. A prospective, randomized, placebo-controlled, double blind, crossover trial. Efeito da pimenta vermelha nos sintomas de pacientes com fissuras anais agudas.

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